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Risk Factors Associated with Acute Appendicitis in Pregnancy

[ Vol. 17 , Issue. 4 ]


Mojtaba Ahmadinejad, Seyed Mozaffar Hashemi* and Mahnaz Jamee   Pages 339 - 343 ( 5 )


Background: Acute appendicitis has been considered as the most common non-obstetric indication that requires surgical intervention in pregnant women.

Objective: The aim of this study is to compare clinical manifestations and para-clinical indices between pregnant and non-pregnant patients who have undergone appendectomy.

Methods: In this prospective cohort study, 57 pregnant and non-pregnant women presenting appendicitis were compared in terms of diagnostic indicators, histopathological characteristics and laboratory findings.

Results: Periumbilical region was the point of initiation of the pain; however, it was more prominent in non-pregnant women. Similarly, tenderness in RLQ (right lower quadrant) of the abdomen was more detectable in the non-pregnant group, and some of the cases showed no rebound tenderness. Pregnant women with appendicitis presented an abnormal increase in the WBC count.

Conclusion: Pregnancy and appendicitis-related signs and symptoms have similarity among them. Due to pregnancy, the physical examination might not present an exact diagnosis; therefore, pregnant women susceptible to have appendicitis must undergo a complete and careful on-time examination that includes ultrasound and labs.


Acute appendicitis, pregnancy, periumbilical, non-pregnant, obstetric, RLQ.


Department of Surgery, Faculty of Medicine, Alborz University of Medical Sciences, Alborz,, Department of General Surgery, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan,, Student Research Committee, Alborz University of Medical Sciences, Alborz

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