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Is there a Relationship Between Gestational Diabetes and Postpartum Depression?

[ Vol. 17 , Issue. 2 ]


Salman Khazaei, Erfan Ayubi, Saeid Bashirian, Ronak Hamzehei and Ensiyeh Jenabi*   Pages 150 - 155 ( 6 )


Background: The relationship between gestational diabetes and postpartum depression (PPD) is poorly understood and seldom studied.

Objective: In an effort to explore this issue, the present study investigated the relationship between gestational diabetes and PPD.

Methods: The present cross-sectional study was performed on 342 women who were referred to four urban health centers of Hamadan city, west of Iran. We used convenience sampling as a method to recruit women in each health center. We used a researcher-made checklist for gathering data on socio-demographic characteristics and potential risk factors of PPD. The Persian validated version of the Edinburgh Postnatal Depression Scale (EPDS) was used to assess PPD. Univariate and multivariable binary logistic regression was applied to estimate the odds ratio (OR) (95% confidence interval [CI]).

Results: Gestational diabetes was identified as the most important risk factor for PPD with OR (95% CI) of 2.19 (1.11, 4.31); P-value=0.02 after adjusting for other variables. Moreover, the adjusted odds ratio showed that PPD among less-educated women (primary school) was 3.5 times higher compared to women with a university education (OR=3.54, 95% CI: 1.27, 9.84; P-value=0.01).

Conclusion: Our findings suggested that PPD is more likely among women with gestational diabetes and those who are less educated. Interventional and educational activities can be employed to reduce the risk of PPD in this population.


Diabetes, postpartum depression, risk factor, educational activities, interventional activities, Iran.


Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Department of Community Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Social Determinants of Health Research Center, Hamadan University of Medical Sciences, Hamadan, Clinical Research Development Unit of Beheshti Hospital, Hamadan University of Medical Sciences, Hamadan, Autism Spectrum Disorders Research Center, Hamadan University of Medical Sciences, Hamadan

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