Submit Manuscript  

Article Details


Polycystic Ovary Syndrome and Probiotics: A Natural Approach to an Inflammatory Disease

[ Vol. 17 , Issue. 1 ]

Author(s):

Antonio Schiattarella*, Gaetano Riemma, Marco La Verde, Gianluigi Franci, Annalisa Chianese, Diego Fasulo, Michele Fichera, Pasquale Gallo and Pasquale De Franciscis   Pages 14 - 20 ( 7 )

Abstract:


Polycystic ovary syndrome (PCOS) is a condition that affects about 15% of women of reproductive age and is correlated with infertility, insulin resistance, and obesity. The etiology of PCOS is multifactorial and genetic, endocrine, and metabolic causes are involved.

New evidence suggests a link between microorganisms residing in the digestive tracts of humans and the development of PCOS. Moreover, an imbalance in the gut microbial community could be a possible factor for the onset of insulin resistance and obesity. Hyperandrogenism, a key feature of PCOS, could also play a critical role in shaping the microbiome community.

Probiotics could modify the gut microbiota and serve as a potential treatment for PCOS. Here we disclose the association between PCOS and intestinal microbiota and the possible role of probiotics as a new treatment approach.

Keywords:

Polycystic ovary syndrome, PCOS, infertility, probiotics, microbiota, dysbiosis, gut, insulin resistance, natural approach.

Affiliation:

Department of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Naples, Department of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Naples, Department of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Naples, Department of Experimental Medicine, University of Study of Campania “Luigi Vanvitelli”, Naples, Department of Experimental Medicine, University of Study of Campania “Luigi Vanvitelli”, Naples, Department of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Naples, Obstetrics and Gynecology Unit, Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Obstetrics and Gynecology Unit, "Santa Maria delle Grazie" Hospital, Pozzuoli, Naples, Department of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Naples

Graphical Abstract:



Read Full-Text article